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A Phase I follow-up study to RMP-02/MTN-006 that found rectal use of a reduced glycerin formulation of tenofovir gel safe and acceptable among the 60 men and women who took part in the study at three U.S. sites. Based on results, which were first reported February 2012, researchers proceeded with a Phase II trial of reduced glycerin tenofovir gel, MTN-017.

 

See

Gel Safe and Acceptable as Approach to Preventing HIV from Anal Sex in Early Phase Clinical Trial

3-April-2013

 

Reduced Glycerin Formulation of Tenofovir Vaginal Gel Safe for Rectal Use

17-May-2012

 

Rectal Formulation of Tenofovir Gel Found Safe and Acceptable in Early Phase Clinical Study

5-March-2012

 

Promising HIV prevention microbicide tenofovir gel in new trial testing safety of rectal use

13-October-2010

 

MTN-007 Backgrounder

14-March-2012

 

MTN-007 Q&A

14-March-2012

 

Rectal Microbicides – Fact Sheet

1-December-2017

 

See Also

Researchers Reformulate Tenofovir Vaginal Gel for Rectal Use

28-February-2011

 

MTN-007 Study Protocol