Microbicide Trials Network

Studies

Protocol NumberProtocol IDProtocol Title
Concluded
HPTN 03510065Phase II/IIb Safety and Effectiveness Study of the Vaginal Microbicides BufferGel and 0.5% PRO2000/5 Gel (P) for the Prevention of HIV Infection in Women
HPTN 05910145Phase II Expanded Safety and Acceptability Study of the Vaginal Microbicide 1% Tenofovir Gel
Closed to follow Up
MTN-00110617Phase 2 Adherence and Pharmacokinetics Study of Oral and Vaginal Preparations of Tenofovir
MTN-00210600Phase I Study of the Maternal Single-Dose Pharmacokinetics and Placental Transfer of Tenofovir 1% Vaginal Gel among Healthy Term Gravidas
MTN-00410492Phase 1 Study of the Safety and Acceptability of 3% w/w SPL7013 Gel (VivaGelĀ®) Applied Vaginally in Sexually Active Young Women
RMP-02/MTN-00610769Phase 1 rectal microbicide safety and acceptability trial of topically applied tenofovir compared with oral tablet
Enrolling
MTN-00310622Phase 2B Safety and Effectiveness Study of Tenofovir 1% Gel, Tenofovir Disoproxil Fumarate Tablet and Emtricitabine/Tenofovir Disoproxil Fumarate Tablet for the Prevention of HIV Infection in Women
MTN-003B10709Bone Mineral Density Substudy
MTN-003C10746Household and Community Level Factors Associated with Study Product Adherence in VOICE: A Substudy of MTN-003
MTN-00910791Prevalence of HIV-1 Drug Resistance within a Female Screening Population for HIV Prevention Trials
MTN-01510529An Observational Cohort Study of Women following HIV-1 Seroconversion in Microbicide Trials
MTN-01610737HIV Prevention Agent Pregnancy Exposure Registry
Pending
MTN-00510635Expanded Safety and Acceptability Study of a Non-medicated Intravaginal Ring
MTN-00710736A Phase 1 Randomized, Double-Blinded, Placebo-Controlled Rectal Safety and Acceptability Study of Tenofovir 1% Gel
MTN-00810805Expanded Safety of Tenofovir 1% Gel in Pregnancy and Lactation
Withdrawn
MTN-01011682Phase 2 Expanded Safety Study of UC781 0.25% Gel Used Daily Among Sexually Active Women
In development
MTN-012/IPM 01011771Male Tolerance Study of Dapivirine Gel Following Multiple Topical Penile Exposures