VOICE (MTN-003)

The VOICE Study – Vaginal and Oral Interventions to Control the Epidemic – is evaluating the safety and effectiveness of two antiretroviral (ARV)-based approaches for preventing sexual transmission of HIV in women as well as determining which of these women are more likely to follow: applying vaginal gel daily or taking an ARV tablet once a day. VOICE also includes two sub-studies: VOICE B (Bone Mineral Density) and VOICE C (Household and Community Factors Associated with Adherence).

See

VOICE Study, a major HIV prevention trial for women, is launched in Zimbabwe [1]

NIAID Press Release on start of VOICE [2]

Sep 16, 2009

HIV prevention trial of ARV-based strategies to begin next month [3]

Jul 20, 2009

VOICE Backgrounder [4]

VOICE Fact Sheet [5]

VOICE Q&A [6]

Products Fact Sheet [7]

VOICE B (Bone Mineral Density Sub-study)

VOICE B Backgrounder [8]

VOICE B Q&A [9]

Understanding Resistance

Drug Resistance and ARV-Based Prevention Fact Sheet [10]

Drug Resistance and ARV-Based Prevention Q&A [11]

Diagrams:

Video: Drug Resistance and ARV-Based Prevention [15]

See Also

Pre-Exposure Prophylaxis (PrEP) Fact Sheet [16]

MTN-003 (VOICE) Study Protocol [17]

MTN-003 B (VOICE B) Study Protocol [18]

MTN-003 C (VOICE C) Study Protocol [19]

Links:
[1] http://www.mtnstopshiv.org/node/1416
[2] http://www3.niaid.nih.gov/news/newsreleases/2009/VOICE.htm
[3] http://www.mtnstopshiv.org/node/1085
[4] http://www.mtnstopshiv.org/news/studies/mtn003/backgrounder
[5] http://www.mtnstopshiv.org/node/2003
[6] http://www.mtnstopshiv.org/news/studies/mtn003/qa
[7] http://www.mtnstopshiv.org/news/studies/mtn003/facts
[8] http://www.mtnstopshiv.org/news/studies/mtn003b/backgrounder
[9] http://www.mtnstopshiv.org/news/studies/mtn003b/qa
[10] http://www.mtnstopshiv.org/news/studies/mtn003/drfacts
[11] http://www.mtnstopshiv.org/news/studies/mtn003/drqa
[12] http://www.mtnstopshiv.org/sites/default/files/attachments/Diagram_1_finalWhat is resistance.pdf
[13] http://www.mtnstopshiv.org/sites/default/files/attachments/Diagram_2_finalResistance and ART.pdf
[14] http://www.mtnstopshiv.org/sites/default/files/attachments/DIAGRAM 3_finalPrecautions in VOICE.pdf
[15] http://www.mtnstopshiv.org/node/1586
[16] http://www.mtnstopshiv.org/news/studies/mtn003/prep
[17] http://www.mtnstopshiv.org/sites/default/files/attachments/MTN-003 Version 1 0 22MAY2008.pdf
[18] http://www.mtnstopshiv.org/sites/default/files/attachments/MTN-003B BMD Substudy Draft Version 1.0 14July2008 -final-2-clean.pdf
[19] http://www.mtnstopshiv.org/sites/default/files/attachments/MTN-003C Version 1 0-15JULY09.pdf