Microbicide Trials Network

MTN-043

Details

Protocol Title: 
Open Label, Pharmacokinetic, Mother-infant Pair Study of Dapivirine Vaginal Ring Use in Breastfeeding
Status: 
In Development

Description

MTN-043 is an open label, multi-site, mother-infant pair PK study designed to assess the PK of the dapivirine VR when used during breastfeeding. Approximately 100 healthy, HIV-uninfected breastfeeding women and their healthy infants between 6-12 weeks old (inclusive) will be enrolled in MTN-043.

 

Enrolled maternal participants will be on study product for approximately 12 weeks, and enrolled mother-infant pairs will be followed up for up to three and a half months.