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A workshop hosted by the MTN in January at the 2018 African American MSM Leadership Conference on Health Disparities and Social Justice (NAESM 2018) addressed where rectal microbicide research is heading and why on demand, non-systemic products may represent important options for HIV prevention through anal sex. Attendees of the workshop, Flirt, Insert & Squirt: Developing rectal microbicides for YOUR sex life, participated in a group activity to develop messaging around three potential HIV prevention products (rectal douches, suppositories and inserts) whose acceptability will be explored as placebo products in an upcoming MTN study. The study, MTN-035, is expected to launch later in 2018.