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A Phase I safety study of the dapivirine vaginal ring in adolescent girls that was conducted at six U.S. research sites from 2013 to 2016 in collaboration with the National Institutes of Health-funded Adolescent Medicine Trials Network (ATN) for HIV/AIDS Interventions. The study enrolled 96 girls ages 15-17 at six U.S. sites who were randomly assigned to use either the dapivirine ring or a placebo ring each month for six months.  Results, which were presented at IAS 2017, found no differences in safety outcomes between the dapivirine ring and the placebo ring. Ring acceptability and adherence to ring use were also high.

 

Researchers present additional evidence on the safety of the dapivirine vaginal ring

for HIV prevention in women

23-October-2018

 

Dapivirine ring studies in adolescent girls and young women - Q&A

12-October-2017

 

HIV prevention dapivirine vaginal ring found safe and acceptable in US adolescent girls

25-July-2017

 

See Also

MTN-023/IPM 030 Protocol

 

MTN-023/IPM 030 Study Page

 

About the REACH Study (MTN-034)